PolyQ Disease: Too Many Qs, Too Much Function?
نویسندگان
چکیده
منابع مشابه
PolyQ Disease: Too Many Qs, Too Much Function?
The nature of the gain-of-function toxicity found in polyglutamine (polyQ) diseases has been the subject of considerable debate. In this issue of Neuron, Duvick et al. and Nedelsky et al. show that, in two of these diseases, pathology is mediated by normal protein activity.
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ژورنال
عنوان ژورنال: Neuron
سال: 2010
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2010.09.012